67 research outputs found

    Intellectual engagement and cognitive ability in later life (the "use it or lose it" conjecture) : Longitudinal, prospective study

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    Data sharing: All data are available by application to the Aberdeen Birth Cohort steering group (https://www.abdn.ac.uk/birth-cohorts/1921/for-researchers/).Peer reviewedPublisher PD

    Tau Aggregation Inhibitor Therapy : An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Disease

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    ACKNOWLEDGMENTS We thank patients and their caregivers for their participation in the study and are indebted to all the investigators involved in the study, particularly Drs. Douglas Fowlie and Donald Mowat for their helpful contributions to the clinical execution of the study in Scotland. We thank Sharon Eastwood, Parexel, for assistance in preparing initial drafts of the manuscript. We acknowledge constructive comments provided by Professors G. Wilcock and S. Gauthier on drafts of the article. CMW, CRH, and JMDS are officers of, and hold beneficial interests in, TauRx Therapeutics. RTS, PB, KK, and DJW are paid consultants to TauRx Therapeutics. The study was financed entirely by TauRx TherapeuticsPeer reviewedPublisher PD

    Cortical Thickness and Surface Area Networks in Healthy Aging, Alzheimer’s Disease and Behavioral Variant Fronto-Temporal Dementia

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    Acknowledgments We would like to acknowledge the support of the Maxwell compute cluster funded by the University of Aberdeen. We also gratefully acknowledge study investigators and the generosity of study participants.Peer reviewedPublisher PD

    Fuzzy approximate entropy analysis of resting state fMRI signal complexity across the adult life span

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    Acknowledgment The authors would like to acknowledge the work of the International Consortium for Brain Mapping (ICBM) fMRI community in creating the resting state database and making it publicly available within the framework of the 1000 Functional Connectomes project (https://www.nitrc.org/projects/fcon_1000/). M.O. Sokunbi was supported by an MRC grant G1100629.Peer reviewedPreprin

    Cognitive Test Scores and Progressive Cognitive Decline in the Aberdeen 1921 and 1936 Birth Cohorts

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    Acknowledgments: We remain grateful to the kindness of the staff at the Scottish Council for Research in Education who allowed us access to their archive and remained supportive and gracious throughout our collaboration. We thank the many people of Aberdeen who volunteered generously and committed to the long-term success of this program. We thank Victoria Bourne, who made substantial contributions to study design, data collection, data analysis and hypothesis generation. Jen Herbert (deceased) recruited the ABC36 participants, collected data (sessions I and II) and, through her encouragement and professionalism, ensured the continued involvement of many participants. She was much loved by participants and the study team. Funding: The Aberdeen Birth Cohort 1921 and 1936 research program was established in 1997 with funding from the Henry Smith (Kensington Estates) Charity and continued by The UK Biotechnology and Biological Sciences Research Council (1999–2002), The Wellcome Trust (2001–2006), The Scottish Government (2000–2002), the Medical Research Council (2003), Alzheimer Research UK (2002–2005) and the University of Aberdeen Development Trust (2007–2010, 2014).Peer reviewedPublisher PD

    Long-term hydromethylthionine treatment is associated with delayed clinical onset and slowing of cerebral atrophy in a pre-symptomatic P301S MAPT mutation carrier

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    ACKNOWLEDGMENTS We thank the patient for permitting publication of the present report. Authors’ disclosures available online (https://www.j-alz.com/manuscript-disclosures/21-0390r1).Peer reviewedPublisher PD

    The Role of redo-Sentinel Lymph Node Biopsy in Patients With Prior Ipsilateral Breast Cancer Surgery

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    Acknowledgments There is no funding for this project as this is a retrospective review of our practice. This project did not get any grants or funding in the public, commercial or a none profit sector. Open Access via Elsevier agreement.Peer reviewedPublisher PD

    Motion during Acquisition is Associated with fMRI Brain Entropy

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    This work was funded by the University of Aberdeen Development Trust (DT OL1134), and the Wellcome Trust (104036/Z/14/Z).Peer reviewedPublisher PD

    AI in breast screening mammography : breast screening readers' perspectives

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    Acknowledgements We would like to thank all the survey respondents for their time and input. We would also like to thank the Scottish Breast Radiology Forum (SBRF) and British Society of Breast Radiology (BSBR) for their aid in dissemination of the survey. Furthermore, we would like to thank Dr Rumana Newlands for her advice on how to perform content analysis and report its results. iCAIRD Radiology Collaboration team members: Harrison D (iCAIRD Director), University of St Andrews. Black C, Murray A and Wilde K, University of Aberdeen. Blackwood JD, NHS Greater Glasgow and Clyde. Butterly C and Zurowski J, University of Glasgow. Eilbeck J and McSkimming C, NHS Grampian. Canon Medical Research Europe Ltd. – SHAIP platform. Funding This work is supported by the Industrial Centre for Artificial Intelligence Research in Digital Diagnostics (iCAIRD) which is funded by Innovate UK on behalf of UK Research and Innovation (UKRI) [project number: 104690]. The funding source was not involved in study design; collection, analysis and interpretation of data; writing of the report; or in the decision to submit the article for publication. Author infoPeer reviewedPublisher PD
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